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Chapter 21 of 92Space & aerospace1 min read · 0 exhibits

Ageing, Bone and Muscle Models

Why is microgravity useful for studying ageing, bone loss and muscle wasting, and is there a commercial market?

Chapter summary

astronauts lose bone and muscle rapidly in orbit, and cells and tissues show changes resembling accelerated ageing.

Key takeaways

  1. 1

    That makes orbit a fast laboratory for diseases such as osteoporosis and sarcopenia.

  2. 2

    Helogen plans a 30-day mission with University College London to build a bone model in orbit, claiming data that would take about three years on Earth; NASA and NIH have supported tissue-chip studies on the ISS.

  3. 3

    The market is research services for drug discovery, similar to organoids (Chapter 20), with no product approval needed.

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